Mechanisms of thymus homing
نویسندگان
چکیده
منابع مشابه
Mechanisms of thymus medulla development and function.
The development of CD4(+) helper and CD8(+) cytotoxic T-cells expressing the αβ form of the T-cell receptor (αβTCR) takes place in the thymus, a primary lymphoid organ containing distinct cortical and medullary microenvironments. While the cortex represents a site of early T-cell precursor development, and the positive selection of CD4(+)8(+) thymocytes, the thymic medulla plays a key role in t...
متن کاملMechanisms of thymus organogenesis and morphogenesis.
The thymus is the primary organ responsible for generating functional T cells in vertebrates. Although T cell differentiation within the thymus has been an area of intense investigation, the study of thymus organogenesis has made slower progress. The past decade, however, has seen a renewed interest in thymus organogenesis, with the aim of understanding how the thymus develops to form a microen...
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Many dendritic cells (DCs) in the normal mouse thymus are generated intrathymically from common T cell/DC progenitors. However, our previous work suggested that at least 50% of thymic DCs originate independently of these progenitors. We now formally demonstrate by parabiotic, adoptive transfer, and developmental studies that two of the three major subsets of thymic DCs originate extrathymically...
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Besides having a well-developed vestibular system, pigeons possess a gravity and inertia sensitive system mediated by displacement of the viscera, presumed to stimulate mesenteric mechanoreceptors. Classical conditioning experiments confirm a sensitivity to atmospheric pressure changes. Failure to demonstrate a magnetic field orientation sensitivity in an instrumental conditioning situation is ...
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© 2016 TERRAPUB, Tokyo. All rights reserved. doi:10.5047/absm.2016.00901.0001 pink salmon are phylogenetically the most advanced salmon species, while masu salmon are considered to be the more primitive species (Murata et al. 1996). Pink salmon are also the most widely distributed species and have the largest population size, while masu salmon appear to have the most restricted distribution and...
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ژورنال
عنوان ژورنال: Blood
سال: 1993
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v81.1.1.1